![]() ![]() Fibrosis, alone cannot be sufficient to make diagnosis of chronic appendicitis as the amount of fibrous tissue in the appendix normally increases with age, as the lymphoid tissue regresses. Criteria for diagnosis of chronic appendicitis were evidence of chronic inflammation with infiltration of the muscle coat & serosa by lymphocytes & plasma cells. Omotoso A J et al, 81 Kulkarni MP et al 69 reported frequency of chronic appendicitis as 48.0 % and 47.02% respectively, our study is comparable with these studies. The most common affliction was chronic non specific appendicitis (48.27%) followed by acute appendicitis (47.80%). In cases of acute appendicitis with perforation peritonitis microscopic examination revealed areas of myonecrosis along with above findings ( Figure 2b). On microscopic examination the mucosa showed ulceration and the wall of the appendix showed diffuse and dense infiltration by polymorphs and mononuclear cells. In 26 cases the external surfaces were covered with exudate and 62 showed sealed off perforation ( Figure 2a) which were in the range 0.5-1.5cm and 1-2 cms away from the tip. On gross examination of 522 specimens most of the appendices were swollen and turgid. The patients presented with complaints of fever, nausea, vomiting and right iliac fossa pain. Most of the cases of acute appendicitis with or without periappendicitis were seen in the age group of 21-30 years (39.63%) with slight male preponderance.Īcute appendicitis with perforation peritonitis (35.44%) was more common in the age group of 0-10 years and 71-80 years and was more frequent in males. 4 shows age and sex distribution of cases of acute appendicitis with or without periappendicitis. Out of 522 cases of acute appendicitis, most commonly encountered cases were of acute appendicitis with or without periappendicitis (63.79%) followed by acute appendicitis with perforation peritonitis (35.44%). Table 3 shows Distribution of cases of acute appendicitis. The various lesions of appendix clinically present as acute or chronic appendicitis but histology reveals the true nature of the lesion and hence remains the gold standard method. Neoplastic lesions seen were low grade mucinous neoplasm (0.18) and serrated adenoma (0.09).Ĭonclusion: Chronic non-specific appendicitis is the commonest appendiceal lesion. Other non neoplastic lesions found were fibrous obliteration of appendix (2.10%), chronic appendicitis with Enterobius vermicularis infestation (0.83), tuberculosis (0.18), xanthogranulomatous appendicitis (0.09%) and amoebic appendicitis (0.09%). The commonest lesion was chronic non-specific appendicitis (48.27%) followed by acute appendicitis with (47.80%). ![]() Results: The study included 1092 cases of lesions of appendix. Special stains were used wherever required. The histopathological reports and clinical details were collected and slides were reviewed and evaluated. Materials and Methods: It is a retrospective study for a period of three years at Tertiary care hospital. Appendicectomy specimens from suspected acute appendicitis often appear macroscopically normal but histological analysis reveal a more sinister underlying pathology.Ī three year study was performed to determine the incidence of various non-neoplastic and neoplastic lesions of appendix.Īim: To study the histopathology of various lesions of appendix. Acute Appendicitis being the most common surgical emergency. Introduction: The human appendix is a supposedly funtionless organ, but can cause morbidity and mortality because it is likely to be infected. ![]()
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